![]() Despite the encouraging data, it is necessary to broaden the sample of patients and perform the same study with other antibiotics.Ĭhronic wound Daptomicin Negative pressure wound therapy Vacuum Assisted Closure therapy. The preliminary analysis of the data showed an important increase of antibiotic concentration in the tissue after VAC therapy. Statistical differences were not found between the two groups. The results highlighted a significant increase in the concentration of antibiotics in the study group tissue the improvement was sensibly lower in the control group. Fisher's exact test was used to compare the two groups. A control group was enrolled in which patients followed the same protocol, but they were treated with traditional dressings. NPWT is an adjunctive therapy consisting of a non invasive wound closure system that uses controlled negative pressure to promote healing. NPWT was first introduced in North America in 1995. At the end of VAC therapy, a second lesion biopsy was performed and analysed to detect tissue concentration of the drug at time 1. Negative pressure wound therapy (NPWT) is one of these emerging treatments. Afterwards, the patients were subjected to VAC therapy. A biopsy of the lesion was carried out to detect tissue concentration of the drug at time 0. Wide and deep wound defects are a challenge to surgeons, particularly when aggressive or more radical operations are unavailable. They were given antibiotic therapy with daptomycin with a specific protocol. Patients who presented with ulcers infected with daptomycin-sensitive bacteria were eligible to be enrolled in this prospective study. The objective of this study is to extend the indications for VAC therapy to include infected wounds by demonstrating its ability to increase the antibiotic concentration in the damaged and infected tissues. Wound infection is considered a relative contraindication. 67–71.Vacuum-assisted closure (VAC) therapy is a sophisticated system that maintains a closed, humid, sterile and isolated environment. Free tissue reconstruction of the scalp pp. Thieme Medical Publishers New York, NY, USA: 2019. Sokoya M., Misch E., Vincent A., Wang W., Kadakia S., Ducic Y., Smith J. Pressure ulcers from spinal immobilization in trauma patients: A systematic review. ![]() Ham W., Schoonhoven L., Schuurmans M.J., Leenen L.P. Predictors of superficial and severe hospital-acquired pressure injuries: A cross-sectional study using the International Pressure Ulcer Prevalence™ survey. Kayser S.A., VanGilder C.A., Lachenbruch C. An overview of co-morbidities and the development of pressure ulcers among older adults. Jaul E., Barron J., Rosenzweig J.P., Menczel J. Our contemporary understanding of the aetiology of pressure ulcers/pressure injuries. Gefen A., Brienza D.M., Cuddigan J., Haesler E., Kottner J. Negative pressure wound therapy (NPWT) is a broad term used to describe a unique and versatile system that aids the optimization of wound healing through the application of sub-atmospheric pressure to help reduce inflammatory exudate and promote granulation tissue. Local flap negative pressure wound therapy occipital scalp pressure sores split-thickness skin graft. The innovative surgical method incorporating NPWT offers an efficient and safe treatment option for patients with occipital pressure sores, potentially establishing itself as the future gold standard for managing this condition. Conclusions: As the aging population continues to grow, occipital pressure sores have gained significant attention as a crucial medical condition. No significant difference in flap survival rate was observed between the two groups. Results: The NPWT group ( n = 24) demonstrated a significantly higher mean graft take percentage at postoperative day 14 compared with the conventional dressing group (n = 22) (98.2% vs. A comparative analysis was performed between the NPWT group and the conventional dressing group. Surgical outcomes, including flap survival rate, graft take percentage, and complications, were assessed. Material and methods: A retrospective analysis was performed on patients with occipital pressure sores who underwent hybrid reconstructions using a local flap and split-thickness skin graft in conjunction with NPWT. This study aims to evaluate the efficacy and safety of a novel reconstruction method utilizing a local transpositional flap and split-thickness skin graft with negative pressure wound therapy (NPWT) for occipital pressure sore treatment. Surgical management of occipital pressure sores poses unique challenges due to limited elasticity and the spherical shape of the scalp. ![]() Background and objectives: Pressure sores are a common medical burden among patients, particularly those who are bedridden or frail. ![]()
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